🧬 Tumor Maps, AI Ultrasounds & Cooling Vests for Crisis Care

When the Heat Hits Hard

Cryogenx is developing a wearable cooling system that rapidly reduces core body temperature - a potential lifesaver for people in extreme environments like the military or construction. With global heat waves intensifying, this compact, fast-acting tech could help prevent fatal heat stress before it’s too late.

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Sensing the Small Stuff

Medyria’s PyCath device brings micro-level precision to coronary diagnostics during interventional procedures. It’s designed to help physicians spot vascular issues more accurately and in real-time, potentially reducing the need for invasive follow-ups and enabling faster treatment for heart patients.

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Rebalancing the Inflamed Brain

Chronic neuroinflammation is a hidden driver behind conditions like liver disease and Parkinson’s. Umecrine Cognition’s golexanolone could shift that paradigm. This new class of drug aims to normalize brain signaling and restore cognition, especially in diseases where brain fog and fatigue have long been accepted as "normal."

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Preventive Health, Evolved

Numan is building out a broader preventive care platform focused on digital health monitoring, biomarker testing, and personalized advice. The goal? Helping people stay ahead of potential issues before symptoms escalate - and making wellness more consistent and proactive.

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One Cell at a Time

One Biosciences is betting that single-cell tumor profiling is the future of precision oncology. Their OneMap platform dives deep into the tumor’s internal diversity - not just what it is, but how it behaves. That could mean better therapy matching, improved trial outcomes, and more accurate decisions at the clinic level.

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Targeting the Untargetable

Oncomatryx is advancing a new generation of Antibody-Drug Conjugates designed for “immune-cold” cancers - tumors that don’t usually respond to immunotherapy. Their lead candidate, OMTX705, has shown promising results in pancreatic, colorectal, and lung cancers, thanks to a novel way of targeting fibroblast activation proteins.

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Real-Time Help for Complex Diagnoses

Scanvio Medical is developing an AI-powered assistant designed to support clinicians during pelvic ultrasound exams. The tool analyzes imaging data in real-time to help identify signs of endometriosis - a condition that currently demands a high level of clinical expertise to detect. By embedding intelligent support into a standard procedure, Scanvio could help reduce diagnostic delays and improve patient outcomes.

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Digitizing the Lab Slide

Dreampath Diagnostics is rethinking anatomical pathology by transforming how labs manage and trace tissue samples. Their system of scanners, consumables, and software automates archiving and retrieval, reportedly cutting time spent archiving by 83% while reducing errors and improving diagnostic safety. Already active in over 500 labs across nearly 40 countries, their closed-loop system is helping modernize lab infrastructure.

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